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Medical Drugs
A prescription for knowledge – get the facts on the most common Drugs.
Is Caffeine Addiction Genetic?
Caffeine addiction is a very real addiction and continue overuse of caffeine can have a major impact on all of your body systems. Caffeine speeds the body and cau
Caffeine addiction is a very real addiction and continues overuse of caffeine can have a major impact on all of your body systems. Caffeine speeds the body and causes it to work overtime. This can wear out body systems faster and cause them to work ineffectively. As more research is done into caffeine addition, many are wondering if caffeine addiction is genetic. A study published in PLoS Genetics there are two specific genes that determine the caffeine cravings people experience. As expected those who were predisposed to higher caffeine cravings consumed more caffeine. This study opens to the door to understanding more about the metabolism and how caffeine impacts it. This will also allow new avenues for studying how other consumed items are metabolized.
Studies have previously shown the correlation between alcohol and drug addiction and genetics and this is merely a step in that same direction with a different substance. The two genes affected and being studied is known as AHR and CYP1A2. The CYP1A2 gene is the one that interacts directly with the caffeine and the AHR gene regulates the activity in the CYP1A2 gene.
Surveys show that 90% of the world’s population consumes caffeine in some form, most through the consumption of caffeine. Even to the tune of eight to ten cups of coffee per day. The development in this genetic research comes from how people drink coffee, not how it’s metabolized. The metabolic of caffeine consumption in relation to the CYP1A2 gene has been known for some time. Instead scientists are now able to look at the connection between cravings and caffeine. The studies that have been done have been detailed in looking at sources of caffeine including coffee, chocolate, tea and carbonated drinks. Also looked at is the behavioral traits, symptoms and withdrawals from caffeine consumers.
